This program by Chris Klugewicz is another good idea which falls short in practical terms. It works by keeping a list of the sizes of your applications. If the size changes then that application may be infected.
There are two problems with this program. First there is no batch method of checking your disks, each application must be identified and checked individually. This is supposed to be corrected in later versions.
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The second problem with the program is that there are too many programs which modify themselves or are modified by other programs. For instance, anytime a font or DA is added to the System, it would be flagged. Therefore it is nearly impossible to tell a legitimate change from an infection.
